D052216Level 7
Glucagon-Like Peptide 1
**Definition:** A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.
**Tree numbers:** - D06.472.317.680.500.500
**Synonyms:** - GLP-1 - Glucagon-Like Peptide-1
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