Sulfatidosis

**Definition:** A group of inherited metabolic disorders characterized by the intralysosomal accumulation of sulfur-containing lipids (SULFATIDES), including SULFOGLYCOSPHINGOLIPIDS normally found in the MYELIN SHEATH of the brain. These disorders are caused by defective degradative enzymes leading to substrate accumulation (or storage).

**Tree numbers:** - C10.228.140.163.100.435.825.850 - C16.320.565.189.435.825.850 - C16.320.565.398.641.803.925 - C16.320.565.595.554.825.850 - C18.452.132.100.435.825.850 - C18.452.584.563.641.803.925 - C18.452.648.189.435.825.850 - C18.452.648.398.641.803.925 - C18.452.648.595.554.825.850