Fas-Associated Death Domain Protein

**Definition:** A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.

**Tree numbers:** - D12.644.360.024.285.200 - D12.644.360.024.500.124 - D12.644.360.075.421.200 - D12.776.157.057.018.200 - D12.776.157.057.500.124 - D12.776.476.024.320.550 - D12.776.476.024.500.124 - D12.776.476.075.421.200

**Synonyms:** - FADD Protein, Fas-Associating - Fas-Associating Protein with Death Domain - Fas-Associating Protein FADD - MORT1 Protein - Fas Associated Death Domain Protein