Death Domain Receptor Signaling Adaptor Proteins

**Definition:** Intracellular signaling adaptor proteins that contain DEATH EFFECTOR DOMAINS and bind to the cytoplasmic DEATH DOMAIN region found on DEATH DOMAIN RECEPTORS. Many of the proteins in this class take part in intracellular signaling involving TUMOR NECROSIS FACTOR RECEPTORS.

**Tree numbers:** - D12.644.360.024.285 - D12.644.360.075.421 - D12.776.157.057.018 - D12.776.476.024.320 - D12.776.476.075.421

**Synonyms:** - Death Inducing Signaling Complex Proteins - DED Signaling Adaptor Proteins - Death Effector Domain Signaling Adaptor Proteins