Edar-Associated Death Domain Protein

**Definition:** A tumor necrosis factor receptor-associated factor that acts as a specific signaling adaptor protein for the EDAR RECEPTOR and plays an important role in ectodermal development. It binds to edar receptor via its C-terminal death domain region and to other specific TNF receptor-associated factors via its N-terminal domain. Loss of function of edar-associated death domain protein is associated with AUTOSOMAL RECESSIVE ANHIDROTIC ECTODERMAL DYSPLASIA.

**Tree numbers:** - D12.644.360.024.285.100 - D12.644.360.024.500.061 - D12.644.360.075.421.100 - D12.776.157.057.018.100 - D12.776.157.057.500.061 - D12.776.476.024.320.100 - D12.776.476.024.500.061 - D12.776.476.075.421.100

**Synonyms:** - Edaradd Protein