CRADD Signaling Adaptor Protein

**Definition:** A death domain receptor signaling adaptor protein that plays a role in signaling the activation of INITIATOR CASPASES such as CASPASE 2. It contains a death domain that is specific for RIP SERINE-THEONINE KINASES and a caspase-binding domain that binds to and activates CASPASES such as CASPASE 2.

**Tree numbers:** - D12.644.360.024.131.186 - D12.644.360.024.285.050 - D12.644.360.024.500.050 - D12.644.360.075.358.186 - D12.644.360.075.421.050 - D12.776.157.057.006.186 - D12.776.157.057.018.050 - D12.776.157.057.500.050 - D12.776.476.024.139.186 - D12.776.476.024.320.050 - D12.776.476.024.500.050 - D12.776.476.075.358.186 - D12.776.476.075.421.050

**Synonyms:** - Caspase and Rip Adaptor with Death Domain Protein - RIP-Associated Protein With a Death Domain - RAIDD Signaling Adaptor Protein