CARD Signaling Adaptor Proteins

**Definition:** A family of intracellular signaling adaptor proteins that contain CASPASE ACTIVATION AND RECRUITMENT DOMAINS (CARD). They play a role in APOPTOSIS-related signal transduction by associating with other CARD domain-containing members and activating INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.

**Tree numbers:** - D12.644.360.024.131 - D12.644.360.075.358 - D12.776.157.057.006 - D12.776.476.024.139 - D12.776.476.075.358

**Synonyms:** - Caspase Activation and Recruitment Domain Signaling Proteins