Nod1 Signaling Adaptor Protein

**Definition:** A NOD-signaling adaptor protein that contains a C-terminal leucine-rich domain which recognizes bacterial PEPTIDOGLYCAN. It signals via an N-terminal caspase recruitment domain that interacts with other CARD SIGNALING ADAPTOR PROTEINS such as RIP SERINE-THEONINE KINASES. It plays a role in the host defense response by signaling the activation of CASPASES and the MAP KINASE SIGNALING SYSTEM.

**Tree numbers:** - D12.644.360.024.131.249 - D12.644.360.024.313.249 - D12.644.360.075.358.249 - D12.644.360.539.500.249 - D12.776.157.057.006.249 - D12.776.157.057.078.249 - D12.776.476.024.139.249 - D12.776.476.024.391.249 - D12.776.476.075.358.249

**Synonyms:** - CARD4 Protein - Caspase Recruitment Domain Protein 4 - Nucleotide Oligomerization Domain 1 Protein