Nuclear Receptor Subfamily 1, Group F, Member 1

**Definition:** A DNA-binding orphan nuclear receptor that positively regulates expression of ARNTL TRANSCRIPTION FACTORS and is a regulatory component of the circadian clock system. The protein also has a role in neuron cell survival and differentiation in that loss of function mutations of its gene result in the mouse phenotype referred to as the STAGGERER MOUSE.

**Tree numbers:** - D12.776.260.643.100 - D12.776.476.156.437 - D12.776.826.209.100

**Synonyms:** - Nuclear Receptor ROR-alpha - RAR-Related Orphan Receptor A - Retinoid-Related Orphan Receptor-alpha - Nuclear Receptor NR1F1