Orphan Nuclear Receptors

**Definition:** A broad category of receptor-like proteins that may play a role in transcriptional-regulation in the CELL NUCLEUS. Many of these proteins are similar in structure to known NUCLEAR RECEPTORS but appear to lack a functional ligand-binding domain, while in other cases the specific ligands have yet to be identified.

**Tree numbers:** - D12.776.260.643 - D12.776.826.209 - D12.776.930.645

**Synonyms:** - Orphan Nuclear Receptor