Nuclear Receptor Subfamily 2, Group C, Member 1

**Definition:** A DNA-binding orphan nuclear receptor that has specificity for directly repeated (DR) AGGTCA sequences. It binds DNA as either as a homodimer or as a heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 2. The protein was originally identified as a PROSTATE-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.

**Tree numbers:** - D12.776.260.643.255 - D12.776.826.209.255

**Synonyms:** - Nuclear Receptor NR2C1 - Nuclear Receptor TR2 - Orphan Nuclear Receptor NR2C1 - Orphan Nuclear Receptor TR2 - TR2-11 Receptor