Nuclear Receptor Subfamily 2, Group C, Member 2

**Definition:** An orphan nuclear receptor that has specificity for hormone response elements found in the promoters of target genes. It binds DNA either as a homodimer or as heterodimer with the closely-related orphan nuclear receptor NUCLEAR RECEPTOR SUBFAMILY 2, GROUP C, MEMBER 1. The protein was originally identified as a TESTES-specific protein and is involved in the regulation of variety of cellular processes, including CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS.

**Tree numbers:** - D12.776.260.643.327 - D12.776.826.209.327

**Synonyms:** - Nuclear Receptor NR2C2 - Orphan Nuclear Receptor TR4 - TAK1 Receptor - Testicular Receptor 4 - TR4 Nuclear Hormone Receptor