World Of Taxonomy
D060890Level 5

B7-H1 Antigen

**Definition:** An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.

**Tree numbers:** - D12.776.465.625 - D12.776.467.150.300 - D12.776.543.095.300 - D23.050.301.285.400 - D23.529.168.300

**Synonyms:** - Programmed Death Ligand 1 - Antigens, CD274 - Programmed Cell Death 1 Ligand 1 - B7-H1 Immune Costimulatory Protein - B7H1 Immune Costimulatory Protein - PD-L1 Costimulatory Protein - Programmed Cell Death 1 Ligand 1 Protein - PD-L1 Protein - CD274 Antigen

GET/api/v1/systems/mesh/nodes/D060890
Official DownloadPublic Domain (US Government)Source

Hierarchy Explorer

Loading...

Cross-system equivalences0

No cross-system equivalences mapped for this node.