CTLA-4 Antigen

**Definition:** An inhibitory T CELL receptor that is closely related to CD28 ANTIGEN. It has specificity for CD80 ANTIGEN and CD86 ANTIGEN and acts as a negative regulator of peripheral T cell function. CTLA-4 antigen is believed to play role in inducing PERIPHERAL TOLERANCE.

**Tree numbers:** - D12.776.465.782 - D12.776.543.750.705.222.750 - D23.050.301.264.894.158 - D23.101.100.894.158

**Synonyms:** - CTLA-4 Protein - Cytotoxic T-Lymphocyte Antigen 4 - Antigens, CD152 - CD152 Antigen - Cytotoxic T-Lymphocyte-Associated Antigen 4