D061566Level 8
Voltage-Gated Sodium Channels
**Definition:** A family of membrane proteins that selectively conduct SODIUM ions due to changes in the TRANSMEMBRANE POTENTIAL DIFFERENCE. They typically have a multimeric structure with a core alpha subunit that defines the sodium channel subtype and several beta subunits that modulate sodium channel activity.
**Tree numbers:** - D12.776.157.530.400.875.750 - D12.776.543.550.450.875.750 - D12.776.543.585.400.875.750 - D12.776.631.960
**Synonyms:** - Voltage-Gated Sodium Channel - Sodium Channels, Voltage-Gated
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