NAV1.1 Voltage-Gated Sodium Channel

**Definition:** A voltage-gated sodium channel subtype that is predominantly expressed in the CENTRAL NERVOUS SYSTEM. Defects in the SCN1A gene which codes for the alpha subunit of this sodium channel are associated with DRAVET SYNDROME, generalized epilepsy with febrile seizures plus, type 2 (GEFS+2), and familial hemiplegic migraine type 3.

**Tree numbers:** - D12.776.157.530.400.875.750.100 - D12.776.543.550.450.875.750.100 - D12.776.543.585.400.875.750.100 - D12.776.631.960.100

**Synonyms:** - Voltage-Gated Sodium Channel Type 1 - Type 1 Voltage-Gated Sodium Channel