Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome

**Definition:** A highly evolutionarily conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc subunits 6, 7, and 8, have been shown to mediate protein-protein interactions, suggesting that Apc3 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to co-activators and APC-C inhibitors.

**Tree numbers:** - D08.811.464.938.750.092.875 - D12.776.167.024.875

**Synonyms:** - Anapc3 - Apc3 Subunit, Anaphase-Promoting Complex - CDC27 Protein