Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome

**Definition:** Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting complex-cyclosome. It binds the Apc2 subunit, which is a part of the catalytic core, and interacts with coactivators Cdh1 or Cdc20 to recruit substrates to the complex.

**Tree numbers:** - D08.811.464.938.750.092.625 - D12.776.167.024.625

**Synonyms:** - Anapc10 - Apc10 Subunit, Anaphase-Promoting Complex