Cytochrome P-450 CYP1B1

**Definition:** A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.

**Tree numbers:** - D08.244.453.005.500 - D08.244.453.100.875 - D08.811.682.690.708.170.010.500 - D08.811.682.690.708.170.020.875 - D12.776.422.220.453.010.500 - D12.776.422.220.453.100.875

**Synonyms:** - Cytochrome P450 CYP1B1 - Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 - Cytochrome P4501B1