Aryl Hydrocarbon Hydroxylases

**Definition:** A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.

**Tree numbers:** - D08.244.453.005 - D08.811.682.690.708.170.010 - D12.776.422.220.453.010

**Synonyms:** - Microsomal Monooxygenases