Cytochrome P-450 CYP2B6

**Definition:** A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is due to the high rate of GENETIC POLYMORPHISMS. Examples of drugs metabolized by CYP2B6 include BUPROPION; efavirenz; CYCLOPHOSPHAMIDE; and MEPERIDINE.

**Tree numbers:** - D08.244.453.005.575 - D08.244.453.491.344 - D08.811.682.690.708.170.010.575 - D08.811.682.690.708.170.450.344 - D12.776.422.220.453.010.575 - D12.776.422.220.453.491.344

**Synonyms:** - CYP2B6 - CYPIIB6 - Cytochrome P450 2B6 - 1,4-Cineole 2-exo-Monooxygenase