Cytochrome P-450 CYP2C8

**Definition:** A liver microsomal cytochrome P450 hydroxylase that oxidizes a broad spectrum of substrates including STEROIDS, FATTY ACIDS, and XENOBIOTICS. Examples of pharmaceutical substrates for CYP2C8 include; PACLITAXOL; torsemide; and; AMODIAQUINE

**Tree numbers:** - D08.244.453.005.590 - D08.244.453.491.368 - D08.811.682.690.708.170.010.590 - D08.811.682.690.708.170.450.360 - D12.776.422.220.453.010.590 - D12.776.422.220.453.491.360

**Synonyms:** - CYP2C8 - CYPIIC8 - Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 - S-Mephenytoin 4-Hydroxylase - Cytochrome P450 MP-20