Rho Guanine Nucleotide Exchange Factor 2

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Rho guanine nucleotide exchange factor 2 (986 aa, ~112 kDa) is encoded by the human ARHGEF2 gene. This protein is involved in the regulation of both guanine nucleotide exchange and signal transduction.

**Synonyms:** - ARHGEF2 - GEF-H1 - Guanine Nucleotide Exchange Factor H1 - Microtubule-Regulated Rho-GEF - Proliferating Cell Nucleolar Antigen p40