Cactinomycin

**Semantic type:** Amino Acid, Peptide, or Protein|Antibiotic|Pharmacologic Substance

**Definition:** A chromopeptide antineoplastic antibiotic isolated from the bacterium Streptomyces chrysomallus. Cactinomycin binds to DNA by intercalating between guanine and cytosine, forming stable antibiotic-DNA complexes that inhibit RNA and protein synthesis. (NCI04)

**Synonyms:** - ACTINOMYCIN C - Actinomycin C - CACTINOMYCIN