1-Phosphatidylinositol 4,5-Bisphosphate Phosphodiesterase Gamma-1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (1290 aa, ~149 kDa) is encoded by the human PLCG1 gene. This protein is involved in the intracellular propagation of signals from ligand-dependent receptor-type tyrosine kinases.

**Synonyms:** - EC 3.1.4.11 - Inositoltrisphosphohydrolase Monophosphatidylinositol Phosphodiesterase - PLC-148 - PLC-Gamma-1 - PLC-II - PLCG1 - Phosphatidylinositol Phospholipase C - Phosphoinositidase C - Phosphoinositide Phospholipase C - Phosphoinositide Phospholipase C-Gamma-1 - Phospholipase C-148 - Phospholipase C-Gamma-1 - Phospholipase C-II - Triphosphoinositide Phosphodiesterase