Hydrolase

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Enzymes (EC class 3) cleaving substrates with addition of H2O at the point of cleavage; e.g., esterases, phosphatases, nucleases, peptidases. SYN hydrolyzing enzymes.

**Synonyms:** - EC 3 - Hydrolases