CBFA2T2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CBFA2T2 wild-type allele is located in the vicinity of 20q11 and is approximately 160 kb in length. This allele, which encodes protein CBFA2T2, may play a role in tumor suppression. This gene is frequently fused to RUNX1 by the t(8;21)(q22;q22) translocation in acute myeloid leukemia.

**Synonyms:** - Core-Binding Factor, Runt Domain, Alpha Subunit 2; Translocated to, 2 wt Allele - EHT - MTGR1 - ZMYND3