E3 Ubiquitin-Protein Ligase Makorin-1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 ubiquitin-protein ligase makorin-1 (482 aa, ~53 kDa) is encoded by the human MKRN1 gene. This protein is involved in the ubiquitination of proteins that regulate both cell survival and gene expression.

**Synonyms:** - EC 2.3.2.27 - EC 6.3.2.-, Formerly - Makorin 1 - Makorin Ring Finger Protein 1 - Makorin-1 - RING Finger Protein 61