E3 Ubiquitin-Protein Transferase

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** An ATP-dependent aminoacyltransferase that catalyzes the third step in the ubiquitination reaction via the transfer of ubiquitin from an E2 ubiquitin-conjugating enzyme to lysine residues found in the final substrate protein.

**Synonyms:** - E3 Ubiquitin Ligase - E3 Ubiquitin Transferase - E3 Ubiquitin-Protein Ligase