Eniluracil/5-FU Combination Tablet

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A combination tablet of ethynyluracil and fluorouracil. Fluorouracil is an antimetabolite fluoropyrimidine analog of the nucleoside pyrimidine with antineoplastic activity. Ethynyluracil is an orally-active fluoropyrimidine analog that inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil in the liver. This may lead to an increase in the bioavailability and, effectiveness of fluorouracil.

**Synonyms:** - 776C85/5-FU - Ethynyluracil/Fluorouracil - GW776/5-FU - GW776/5-Fluorouracil