Beta-Secretase 1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Beta-secretase 1 (501 aa, ~56 kDa) is encoded by the human BACE1 gene. This protein plays a role in the proteolysis of ectodomains of membrane proteins.

**Synonyms:** - APP Beta-Secretase - ASP2 - Asp 2 - Aspartyl Protease 2 - BACE1 - Beta-Site APP Cleaving Enzyme 1 - Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme - Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme 1 - Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 - EC 3.4.23.46 - Memapsin 2 - Memapsin-2 - Membrane-Associated Aspartic Protease 2 - Transmembrane Aspartic Proteinase Asp2