Serine/Threonine-Protein Kinase/Endoribonuclease IRE1

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Serine/threonine-protein kinase/endoribonuclease IRE1 (977 aa, ~110 kDa) is encoded by the human ERN1 gene. This protein is involved in both protein phosphorylation and mRNA processing in response to endoplasmic reticulum stress-dependent signaling.

**Synonyms:** - ERN1 - Endoplasmic Reticulum-To-Nucleus Signaling 1 - IRE1a - Inositol-Requiring Enzyme 1 - Inositol-Requiring Protein 1 - Ire1-alpha - hIRE1p