EGFR Exon 19 Deletion Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** In-frame deletions occurring within the exon 19-encoded part of the epidermal growth factor receptor (EGFR) kinase domain. These mutations are commonly seen in non-small cell lung cancer and are associated with increased sensitivity to EGFR tyrosine kinase inhibitors.

**Synonyms:** - EGFR DEL19 - EGFR DEL19 Mutation - EGFR Ex19Del - EGFR Exon 19 Gene Deletion Mutation - EGFR del19 - ERBB Exon 19 Deletion Mutation - ERBB1 Exon 19 Deletion Mutation - Epidermal Growth Factor Receptor Gene Exon 19 Deletion Mutation - Ex19Del - Exon 19 Deletion - HER1 Exon 19 Deletion Mutation