Ubiquitin Carboxyl-Terminal Hydrolase 22

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Ubiquitin carboxyl-terminal hydrolase 22 (525 aa, ~60 kDa) is encoded by the human USP22 gene. This protein plays a role in the deubiquitination of histones H2A and H2B.

**Synonyms:** - Deubiquitinating Enzyme 22 - EC 3.4.19.12 - USP22 - Ubiquitin Specific Peptidase 22 - Ubiquitin Specific Peptidase 3-Like - Ubiquitin Specific Protease 22 - Ubiquitin Thioesterase 22 - Ubiquitin Thiolesterase 22 - Ubiquitin-Specific Processing Protease 22 - Ubiquitin-Specific Protease 22 - Ubiquitin-Specific-Processing Protease 22