Aminothiadiazole

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic derivative of nicotinamide adenine dinucleotide (NAD). Aminothiadiazole competitively inhibits inosine 5-monophosphate dehydrogenase, thereby disrupting the regulation of cell proliferation and differentiation in a number of cells. This agent is also a selective human adenosine A3 receptor antagonist. (NCI04)

**Synonyms:** - 1,3, 4-Thiadiazol-2-amine (9CI) - 1,3, 4-Thiadiazol-2-amine (9CI) - 1,3, 4-Thiadiazole, 2-Amino- (8CI) - 1,3, 4-Thiadiazole, 2-amino- (8CI) - 1,3,4-Thiadiazole, 2-Amino - 1,3,4-Thiadiazole, 2-amino - 2-AMINO-1,3,4-THIADIAZOLE - 2-Amino-1,3,4-thiadiazole - 2-Amino-1,3,4-thiadiazole - 2-Amino-1-thia-3,4-diazole - 2-Amino-1-thia-3,4-diazole - 2-Aminothiadiazole - 2-Aminothiadiazole - ATDA - Amino 134-Thiadiazole - FDA 0084 - FDA 0084