Inosine Monophosphate Dehydrogenase Inhibitor

**Semantic type:** Chemical Viewed Functionally

**Definition:** Any substance that inhibits inosine monophosphate dehydrogenase, an enzyme that catalyzes the conversion of inosine monophosphate to xanthosine monophosphate, the rate-limiting step in the de novo biosynthesis of guanine nucleotides. Inhibition of inosine monophosphate dehydrogenase can lead to inhibition of cell proliferation.

**Synonyms:** - IMPDH Inhibitors - Inosine 5'-Phosphate Dehydrogenase Inhibitor