Ravtansine

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A tubulin-binding maytansinoid. Ravtansine binds to tubulin at the maytansine-binding site, which disrupts microtubule assembly/disassembly dynamics and inhibits mitosis.

**Synonyms:** - DM 4 - DM-4 - DM4 - MAYTANSINOID DM4 - N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine - N2'-[4-[(3-carboxypropyl)dithio]-4-methyl-1-oxo-2-sulfopentyl]-N2'-deacetylmaytansine