Elliptinium Acetate

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** Acetate salt of elliptinium, a derivative of the alkaloid ellipticine isolated from species of the plant family Apocynaceae, including Bleekeria vitensis, a plant with anti-cancer properties. As a topoisomerase II inhibitor and intercalating agent, elliptinium stabilizes the cleavable complex of topoisomerase II and induces DNA breakages, thereby inhibiting DNA replication and RNA and protein synthesis.

**Synonyms:** - 6H-Pyrido[4, 3-b]carbazolium, 9-hydroxy-2,5,11-trimethyl-acetate (salt) - 9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazolium Acetate (Salt) - 9-Hydroxy-2-methylellipticinium Acetate - 9-Hydroxy-2-methylellipticinium acetate - Celiptium - Celiptium - ELLIPTINIUM ACETATE - N-2-Methyl-9-hydroxyellipticinium Acetate