C1376Level 8

Halichondrin B

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A complex macrolide polyether from marine sponge genera, such as Halichondria, Axinella, Phakellia, and Lissodendoryx that binds to tubulin, thereby inhibiting mitosis. (NCI)

**Synonyms:** - HALICHONDRIN B

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