Double-Expressor Lymphoma

**Semantic type:** Neoplastic Process

**Definition:** A diffuse large B-cell lymphoma characterized by double expression of MYC and BCL2 proteins without MYC and BCL2 gene aberrations. These lymphomas may have a worse prognosis than other diffuse large B-cell lymphomas, not otherwise specified, but they are not as aggressive as the high-grade B-cell lymphomas, with rearrangements of MYC and BCL2 and/or BCL6 genes.

**Synonyms:** - DEL - Double Expressor Lymphoma - Double-Expressing Lymphoma - double expressor lymphoma - double_expressor_lymphoma