RISS Stage I Multiple Myeloma

**Semantic type:** Neoplastic Process

**Definition:** Serum beta-2-microglobulin less than 3.5 mg/L and serum albumin 3.5 g/dL or more and no high-risk cytogenetics and normal LDH. High risk cytogenetics consist of one or more of the following: del17p, t(4;14), or t(14;16). (from AJCC 8th Ed.)

**Synonyms:** - RISS Stage I Plasma Cell Myeloma - Revised International Staging System Stage I Plasma Cell Myeloma