RISS Stage III Multiple Myeloma

**Semantic type:** Neoplastic Process

**Definition:** Serum beta-2-microglobulin 5.5 mg/L or more and high-risk cytogenetics and/or high LDH. High risk cytogenetics consist of one or more of the following: del17p, t(4;14), or t(14;16). (from AJCC 8th Ed.)

**Synonyms:** - RISS Stage III Plasma Cell Myeloma - Revised International Staging System Stage IIII Plasma Cell Myeloma