BRCA2 Biallelic Inactivation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** The presence of mutations in both alleles of the BRCA2 gene that either lead to loss of expression of the BRCA2 protein or result in the translation of an inactive BRCA2 protein.

**Synonyms:** - BRCA2 Biallelic Gene Inactivation - BRCC2 Biallelic Gene Inactivation - BROVCA2 Biallelic Gene Inactivation - Breast Cancer 2 Biallelic Gene Inactivation - Breast Cancer 2, Early Onset Biallelic Gene Inactivation - Breast Cancer Type 2 Susceptibility Biallelic Gene Inactivation - FANCD1 Biallelic Gene Inactivation - XRCC11 Biallelic Gene Inactivation