C142781Level 8
Thoracic NUT Carcinoma
**Semantic type:** Neoplastic Process
**Definition:** A highly aggressive, poorly differentiated carcinoma that arises from the thoracic structures. It is characterized by mutations and rearrangement of the NUT gene. It usually presents at an advanced stage with pleuritic chest pain and pleural effusion, non-productive cough, shortness of breath, and weigh loss.
**Synonyms:** - Thoracic NMC
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