Methionine Aminopeptidase 2

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Methionine aminopeptidase 2 (478 aa, ~53 kDa) is encoded by the human METAP2 gene. This protein plays a role in both the steric hindrance of phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (EIF2S1) and the removal of the amino-terminal methionine from nascent proteins.

**Synonyms:** - EC 3.4.11.18 - EIF-2-Associated p67 Homolog - Eukaryotic Initiation Factor 2-Associated Protein, 67-kD - Initiation Factor 2 Associated 67 kDa Glycoprotein - Initiation Factor 2-Associated 67 kDa Glycoprotein - MAP 2 - METAP2 - MetAP 2 - Methionyl Aminopeptidase 2 - Peptidase M - Testicular Tissue Protein Li 17 - p67 - p67eIF2