E3 Ubiquitin-Protein Ligase RING2

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** E3 ubiquitin-protein ligase RING2 (336 aa, ~38 kDa) is encoded by the human RNF2 gene. This protein is involved in both transcriptional repression and the monoubiquitination of lysine-119 of histone H2A.

**Synonyms:** - EC 2.3.2.27 - HIP2-Interacting Protein 3 - Huntingtin-Interacting Protein 2-Interacting Protein 3 - Protein DinG - RING Finger Protein 1B - RING Finger Protein 2 - RING Finger Protein BAP-1 - RING-Type E3 Ubiquitin Transferase RING2 - RING1b - RNF2