Pyrazoloacridine

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A 9-methoxy acridine compound containing a reducible 5-nitro substituent. Pyrazoloacridine appears to intercalate into DNA and inhibit RNA synthesis, DNA synthesis, and the activities of topoisomerases I and II, thereby causing cytotoxicity. (NCI04)

**Synonyms:** - PYRAZOLOACRIDINE - pyrazoloacridine