Ledoxantrone Trihydrochloride

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The trihydrochloride salt of the anthrapyrazole antineoplastic antibiotic sedoxantrone with potential antineoplastic activity. Ledoxantrone intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis.

**Synonyms:** - 2H-(1)Benzothiopyrano(4,3,2-cd)indazol-8-ol, 5-((2-aminoethyl)amino)-2-(2-(diethylamino)ethyl)-, Trihydrochloride - CI 958 - CI-958 - CI-958 - LEDOXANTRONE TRIHYDROCHLORIDE - Sedoxantrone Trihydrochloride - sedoxantrone trihydrochloride