Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L5

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Ubiquitin carboxyl-terminal hydrolase isozyme L5 (329 aa, ~38 kDa) is encoded by the human UCHL5 gene. This protein plays a role in chromatin modification and the removal of lysine-48-linked polyubiquitin chains from substrate proteins.

**Synonyms:** - EC 3.4.19.12 - INO80 Complex Subunit R - UCHL5 - Ubiquitin C-Terminal Hydrolase L5 - Ubiquitin C-Terminal Hydrolase UCH37 - Ubiquitin Carboxyl-Terminal Esterase L5 - Ubiquitin Carboxyl-Terminal Hydrolase L5 - Ubiquitin Thioesterase L5