Idarubicin Hydrochloride

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The hydrochloride salt of the anthracycline antineoplastic antibiotic idarubicin. Idarubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds

**Synonyms:** - IDARUBICIN HYDROCHLORIDE - IMI-30 - Idamycin - Idamycin PFS - Idarubicin HCl - Idarubicin hydrochloride - SC-33428 - Zavedos